7.78 Methods and Topics in Protein Biochemistry and Biophysics


Class Info

Students read and discuss papers dealing with protein structure and function and biophysical techniques used to characterize biological macromolecules. Topics include cooperativity and allostery, protein folding and misfolding, pathways of macromolecular assembly, molecular motors, and protein design. Methods include CD spectroscopy, isothermal calorimetry, analytical ultracentrifugation, light scattering, and real-time kinetic measurements. Covers theoretical principles behind the techniques. Students complete practical exercises using instrumentation available at MIT.

This class has no prerequisites.

7.78 will not be offered this semester. It will be instructed by R. T. Sauer and T. Schwartz.

This class counts for a total of 12 credits. This is a graduate-level class.

In the Spring 2015 Subject Evaluations, 7.78 was rated 6.3 out of 7.0. You can find more information at the http://www.google.com/search?&q=MIT+%2B+7.78&btnG=Google+Search&inurl=https site.

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