7.41 Principles of Chemical Biology
Spanning the fields of biology, chemistry and engineering, class addresses the principles of chemical biology and its application of chemical and physical methods and reagents to the study and manipulation of biological systems. Topics include bioorthogonal reactions and activity-based protein profiling, small molecule inhibitors and chemical genetics, fluorescent probes for biological studies, and unnatural amino acid mutagenesis. Also covers chemical biology approaches for studying dynamic post-translational modification reactions, natural product biosynthesis and mutasynthesis, and high-throughput drug screening. Students taking the graduate version are expected to explore the subject in greater depth
This class has 7.05 as a prerequisite.
7.41 will be offered this semester (Spring 2018). It is instructed by B. Imperiali.
Lecture occurs 9:30 AM to 11:00 AM on Mondays and Wednesdays in 36-112.
This class counts for a total of 12 credits.
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