7.41 Principles of Chemical Biology

Class Info

Spanning the fields of biology, chemistry and engineering, class addresses the principles of chemical biology and its application of chemical and physical methods and reagents to the study and manipulation of biological systems. Topics include bioorthogonal reactions and activity-based protein profiling, small molecule inhibitors and chemical genetics, fluorescent probes for biological studies, and unnatural amino acid mutagenesis. Also covers chemical biology approaches for studying dynamic post-translational modification reactions, natural product biosynthesis and mutasynthesis, and high-throughput drug screening. Students taking the graduate version are expected to explore the subject in greater depth

This class has 7.05 as a prerequisite.

7.41 will not be offered this semester. It will be available in the Spring semester, and will be instructed by J. K. Weng and B. Imperiali.

This class counts for a total of 12 credits.

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