5.062 Principles of Bioinorganic Chemistry

Class Info

Delineates principles that form the basis for understanding how metal ions function in biology. Includes the choice, uptake and assembly of metal-containing units; metal-induced folding of biomolecules; control of metal ion concentrations in cells; electron-transfer chemistry; atom and group transfer chemistry; protein tuning of metal properties; and applications to diagnosis and treatment of disease. Introduces additional topics to expose students to exciting new advances in the field, such as medicinal application of inorganic chemistry; multi-component enzyme systems (e.g.,nitrogenase, hydrogenase, and photosystem II); and metalloprotein engineering and design (e.g., the conversion by mutagenesis of existing metalloprotein scaffolds to achieve novel functions).

This class has 5.03 as a prerequisite.

5.062 will be offered this semester (Fall 2018). It is instructed by D. Suess.

This class counts for a total of 6 credits. This is a graduate-level class.

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