5.062 Principles of Bioinorganic Chemistry
Delineates principles that form the basis for understanding how metal ions function in biology. Includes the choice, uptake and assembly of metal-containing units; metal-induced folding of biomolecules; control of metal ion concentrations in cells; electron-transfer chemistry; atom and group transfer chemistry; protein tuning of metal properties; and applications to diagnosis and treatment of disease. Introduces additional topics to expose students to exciting new advances in the field, such as medicinal application of inorganic chemistry; multi-component enzyme systems (e.g.,nitrogenase, hydrogenase, and photosystem II); and metalloprotein engineering and design (e.g., the conversion by mutagenesis of existing metalloprotein scaffolds to achieve novel functions).
This class has 5.03 as a prerequisite.
5.062 will be offered this semester (Fall 2017). It is instructed by S. Lippard.
Lecture occurs 10:00 AM to 11:30 AM on Tuesdays and Thursdays in 2-105.
This class counts for a total of 12 credits.
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