20.213 DNA Damage and Genomic Instability

Class Info

Focuses on biochemistry and molecular mechanisms of DNA replication and DNA repair. Analyzes chemistry of DNA damaging events, and analyzes mutagenic and toxic consequences of modifications to DNA structure. Also presents the contrasting perspective that normal DNA processing leads to mutations. Moves from analysis and discussion of key DNA repair pathways to connections between DNA repair and human diseases. Discusses in-depth the chemistry and biochemistry of DNA metabolism. Includes current literature related to the molecular mechanisms of radiation and chemotherapy.

This class has 5.07, and 7.05 as prerequisites.

20.213 will not be offered this semester. It will be available in the Spring semester, and will be instructed by B. P. Engelward.

This class counts for a total of 6 credits. This is a graduate-level class.

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