20.104 Environmental Cancer Risks, Prevention, and Therapy
Analysis of the history of cancer and vascular disease mortality rates in predominantly European- and African-American US cohorts, 1895-2010, to discover specific historical shifts. Shifts identified are explored in terms of contemporaneously changing environmental risk factors: air-, food- and water-borne chemicals; subclinical infections; diet and lifestyles. Role of occupational data identifying general risk factors. Considers the hypotheses that environmental factors affect metakaryotic stem cell mutation rates in fetuses and juveniles and/or the growth rates of preneoplastic stem cells in adults. Interaction of environmental and inherited risks. Introduces the use of metakaryocidal drugs to treat cancer in clinical trials.
Lecture occurs 1:00 PM to 2:30 PM on Tuesdays and Thursdays in 16-220.
This class counts for a total of 12 credits.
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